Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
US5650489A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 19, 1991 |
| Grant date | Jul 22, 1997 |
| Priority date | — |
| Expiry date | Jun 19, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/817
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The instant invention provides a library of bio-oligomers of defined size and known composition, in which the library contains all of the possible sequences of the bio-oligomers, and a method of synthesis thereof. The bio-oligomers of the library may be peptides, nucleic acids, or a combination of the foregoing. The instant invention also provides methods to identify bio-oligomers from a library that demonstrate desired characteristics such as binding, bioactivity and catalytic activity. Thus the instant invention provides a unique and powerful method to identify a useful bio-oligomer sequences from a library more quickly than current state-of-the-art technology allows. Effector molecules for use in treatment or diagnosis of disease are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.