Process for preparing 6-oxo-(6H)-dibenz-[c,e][1,2]-oxaphosphorins (ODOPs)

US5650530A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Hans-Josef Buysch · Krefeld, DE
• Volker Glock · Krefeld, DE
• Bernd Griehsel · Bottrop, DE
• Joachim Komoschinski · Neunburg vorm Wald, DE

Key dates

• Filing date: Sep 12, 1995
• Grant date: Jul 22, 1997
• Expiry date: Sep 12, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/65719
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Optionally substituted ODOP is obtained by reaction of optionally substituted o-phenylphenol with PCl.sub.3 in the presence of Lewis acids at elevated temperature in a first stage, with according to the invention an excess of at least 0.05 mol of PCl.sub.3 per mol of o-phenylphenol being maintained during the entire reaction time, and, after removal of the PCl.sub.3, by hydrolysis in a second stage using 1-2 mol of H.sub.2 O per chlorine equivalent of the product of the first stage at 50.degree.-150.degree. C. and with removal of HCl and residual H.sub.2 O.