Process for the preparation of N-acyl-.alpha.-amino acid derivatives

US5650537A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Matthias Beller · Ostseebad Nienhagen, DE
• Hartmut Fischer · Hofheim, DE
• Thomas Gerdau · Eppstein, DE
• Peter Gross · Saarlouis, DE

Key dates

• Filing date: May 2, 1995
• Grant date: Jul 22, 1997
• Expiry date: May 2, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C231/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of N-acylglycine derivatives of the formula (I) ##STR1## which comprises reacting a carboxylic acid amide with an aldehyde in the presence of a solvent and an acid to give an acylaminomethylol and then carbonylating the acylaminomethylol in the presence of a cobalt carbonyl catalyst.