Interferon regulatory factors 1 and 2 in the diagnosis of tumorigenicity

US5652095A · kind A · utility

Assignees

• The Regents of the University of California · US
• The Regents of the University of New Mexico · US
• Tadatsugu Taniguchi · JP

Inventors

• Tadatsugu Taniguchi · Ibaraki, JP
• Cheryl L. Willman · Albuquerque, US
• Maria Pallavicini · Livermore, US
• Hisashi Harada · Kasai, JP
• Nobuyuki Tanaka · Tokyo, JP

Key dates

• Filing date: Sep 24, 1993
• Grant date: Jul 29, 1997
• Expiry date: Sep 24, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates, in general, to a method of diagnosing tumorigenic mammalian cells or the propensity of a mammalian cell to become tumorigenetic. Additionally, the present invention relates to a cloned cDNA or genomic DNA for reducing the propensity of a cell to become tumorigenic or suppressing tumorigenic phenotype of a cell; a method of reducing the propensity of a cell to become tumorigenic or suppressing the tumorigenic phenotype of a cell; a method of treating a patient suffering from or predisposed to subsequent cancer development; and a method of diagnosing tumorigenic tissue of a human or tissue predisposed to become tumorigenic.