Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materials and methods
US5652131A · kind A · utility
20Cited by
0References
12Claims
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Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Jul 29, 1997 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.