Oxido reductase enzyme system obtainable from P. chrysogenum, the set of genes encoding the same and the use of oxido reductase enzyme systems or genes encoding the same for increasing antibiotic production

US5652132A · kind A · utility

Assignee

• Gist-Brocades B.V. · NL

Inventors

• Yair Aharonowitz · Hod HaSharon, IL
• Lucia Helena Maria Van Der Voort · Delft, NL
• Gerald Cohen · Hod HaSharon, IL
• Roelof Ary Lans Bovenberg · Rotterdam, NL
• Rachel Schreiber · Herzliya, IL
• Anat Argaman · Rosh HaAyin, IL
• Yossef Av-Gay · Vancouver, CA
• Helena Maria Nan · Kaiseraugst, CH
• Alfred Kattevilder · Delft, NL
• Harriet Pa Lissa · Berlin, DE
• Henk Van Liempt · Berlin, DE

Key dates

• Filing date: Jul 12, 1994
• Grant date: Jul 29, 1997
• Expiry date: Jul 12, 2014

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/935
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A new oxido reductase enzyme activity obtainable from P. chrysogenum, involved in the production of .beta.-lactams, the set of genes encoding said enzyme activity, and a method to enhance said production by using the above-mentioned oxido reductase system and other oxido reductase systems or genes encoding for the same have been disclosed.