Patent · US Expired

Method of monitoring patient compliance with medications prescriptions

US5652146A · kind A · utility

33Cited by
9References
6Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJul 5, 1996
Grant dateJul 29, 1997
Priority date
Expiry dateJul 5, 2016

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/173845
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method of monitoring compliance of a patient that has been placed on a medication maintenance program with a prescribed medication dosage by determining a normalized urine medication concentration. An unadulterated urine sample is obtained from the patient. The urine medication concentration and urine specific gravity are measured. The normalized urine medication concentration is calculated as a function of the measured medication concentration in the urine and the urine specific gravity. The calculated normalized urine medication concentration is compared with an expected medication concentration value for the patient for the maintenance program prescribed to determine any significant differences therebetween as an indication of noncompliance. Alternatively, a urinary-parameter normalized urine medication concentration is calculated as a function of the measured medication concentration in the urine, the urine specific gravity and at least one selected pharmacokinetic parameter of the medication. The calculated urinary-parameter normalized urine medication concentration is compared with an expected medication concentration value for an average compliant patient for the maintenan…

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