Aryl substituted heterocycles
US5654299A · kind A · utility
10Cited by
5References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 18, 1994 |
| Grant date | Aug 5, 1997 |
| Priority date | — |
| Expiry date | Apr 18, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention concerns the novel use of aryl substituted heterocycles of formula I, set out below, which antagonize the pharmacological actions of one of ent endogenous neuropeptide tachykinins an the neurokinin 2 (NK2) receptor making them useful whenever such antagonism is desired, such as in the treatment of asthma and related conditions. The invention also provides pharmaceutical compositions containing the aryl substituted heterocycles for use in such treatment. Certain novel aryl substituted heterocycles of formula I and novel intermediates for their manufacture are also provided. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.