Indole piperazine platelet activating factor antagonists
US5654305A · kind A · utility
14Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 2, 1996 |
| Grant date | Aug 5, 1997 |
| Priority date | — |
| Expiry date | Jul 2, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides compounds of formula ##STR1## wherein Y is >C.dbd.O or >S(O).sub.t wherein t is 1 or 2 and the pharmaceutically acceptable salts thereof which are potent antagonists of PAF and are useful in the treatment of PAF-related disorders including asthma, rhinitis, shock, respiratory distress syndrome, acute inflammation, transplanted organ rejection, gastrointestinal ulceration, allergic skin diseases, delayed cellular immunity, parturition, fetal lung maturation, and cellular differentiation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.