Method for the acylation of the 7-amino group of the cephalosporanic ring
US5654425A · kind A · utility
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2References
2Claims
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Key dates
| Filing date | May 1, 1995 |
| Grant date | Aug 5, 1997 |
| Priority date | — |
| Expiry date | May 1, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for the acylation of the 7-amino group of the cephalosporanic ring, according to which a 7-ACA amino thiazolyl protected adduct is prepared by acylating said amino group by an aminothiazolyl acetic acid whose amino group has been protected by a phenyl acetyl or a phenoxy acetyl group, the amino group being then deprotected by aqueous hydrolysis in the presence of penicillin G amidase or respectively penicillin V amidase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.