Patent · US Expired

4,7-dichlorofluorescein dyes as molecular probes

US5654442A · kind A · utility

28Cited by

9References

21Claims

0Family size

Assignee

PerkinElmer, Inc. · US

Inventors

Steven M. Menchen · Fremont, US
Linda G. Lee · Palo Alto, US
Charles R. Connell · Redwood City, US
N. Davis Hershey · Redwood City, US
Vergine Chakerian · San Mateo, US
Sam Woo · Redwood City, US
Steven Fung · Palo Alto, US

Key dates

Filing date	Mar 8, 1995
Grant date	Aug 5, 1997
Priority date	—
Expiry date	Mar 8, 2015

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/147777
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Long wavelength, narrow emission bandwidth fluorecein dyes are provided for detecting spacially overlapping target substances. The dyes comprise 4,7-dichlorofluoresceins, and particularly 2',4',5',7'-tetrachloro-4,7-dichloro-5- (and 6-) carboxyfluoresceins. Methods and kits for using the dyes in DNA analysis are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.