Patent · US Expired

Test device for detecting analytes in biological samples

US5656503A · kind A · utility

265Cited by
156References
64Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 15, 1994
Grant dateAug 12, 1997
Priority date
Expiry dateSep 15, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/818
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An analytical test device useful for example in pregnancy testing, comprises a hollow casing (500) constructed of moisture-impervious solid material, such as plastics materials, containing a dry porous carrier (510) which communicates indirectly with the exterior of the casing via a bibulous sample receiving member (506) which protrudes from the casing such that a liquid test sample can be applied to the receiving member and permeate therefrom to the porous carrier, the carrier containing in a first zone a labelled specific binding reagent is freely mobile within the porous carrier when in the moist state, wherein the mobility is facilitated by a material comprising a sugar, in an amount effective to reduce interaction between the test strip and the labelled reagent, and in a second zone spatially distinct from the first zone unlabelled specific binding reagent for the same analyte which unlabelled reagent is permanently immobilised on the carrier material and is therefore not mobile in the moist state, the two zones being arranged such that liquid sample applied to the porous carrier can permeate via the first zone into the second zone, and the device incorporating means, such as …

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.