Method of enhancing and/or prolonging expression of gene introduced into a cell using colchicine
US5656609A · kind A · utility
20Cited by
2References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 5, 1993 |
| Grant date | Aug 12, 1997 |
| Priority date | — |
| Expiry date | Apr 5, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The expression of polynucleotide introduced into a cell by means of a targeted complex of the polynucleotide linked to a cell-specific binding agent can be enhanced and prolonged by inhibiting translocation or fusion of endosomes to lysosomes using colchicine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.