Substituted benzimidazoles

US5656649A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Winfried Lunkenheimer · Wuppertal, DE
• Bernd Baasner · Bensberg, DE
• Folker Lieb · Leverkusen, DE
• Stefan Bohm · Cologne, DE
• Albrecht Marhold · Leverkusen, DE
• Ulrich Görgens · Ratingen, DE
• Wilhelm Stendel · Wuppertal, DE
• Heinz-Wilhelm Dehne · Monheim, DE
• Hans-Joachim Santel · Leverkusen, DE

Key dates

• Filing date: May 25, 1995
• Grant date: Aug 12, 1997
• Expiry date: May 25, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/65068
• WIPO field: Basic materials chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new substituted benzimidazoles of the general formula (I) ##STR1## in which R.sup.1 represents hydrogen, alkyl, alkoxy or optionally substituted aryl, PA1 R.sup.2 represents hydroxyl, cyano or in each case optionally substituted alkyl, alkenyl, alkinyl, alkoxy, alkenyloxy, alkinyloxy, alkylthio, amino, aminocarbonyl, alkylcarbonyl, alkoxycarbonyl, alkylcarbonyloxy, dialkoxyphosphonyl, (hetero)aryl, (hetero)arylcarbonyl, (hetero)aryloxycarbonyl, (hetero)arylcarbonyloxy or (hetero)arylaminocarbonylaminocarbonyloxy, and PA1 R.sup.3 represents fluoroalkyl, PA1 X.sup.1, X.sup.2, X.sup.3 and X.sup.4 independently of one another in each case represent hydrogen, halogen, cyano, nitro, in each case optionally substituted alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl or cycloalkyl, optionally substituted, fused dioxyalkylene, or represent hydroxycarbonyl, alkylcarbonyl, alkoxycarbonyl or cycloalkyloxycarbonyl, in each case optionally substituted amino or aminocarbonyl or in each case optionally substituted aryl, aryloxy, arylthio, arylsulphinyl, arylsulphonyl, arylsulphonyloxy, arylcarbonyl, aryloxycarbonyl, arylazo or arylthiomethylsulphonyl, but where at…