Miniaturized planar columns in novel support media for liquid phase analysis

US5658413A · kind A · utility

Assignee

• Hewlett-Packard Company, L.P. · US

Inventors

• Patrick Kaltenbach · Bischweier, DE
• Sally A. Swedberg · Santa Cruz, US
• Klaus Witt · Keltern, DE
• Fritz Bek · Remchingen, DE
• Laurie S. Mittelstadt · Belmont, US

Key dates

• Filing date: Jun 7, 1995
• Grant date: Aug 19, 1997
• Expiry date: Jun 7, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T156/1064
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Miniaturized planar column devices are described for use in liquid phase analysis, the devices comprising microstructures fabricated by laser ablation in a variety of novel support substrates. Devices formed according to the invention include associated laser-ablated features required for function, such as analyte detection means and fluid communication means. Miniaturized columns constructed under the invention find use in any analysis system performed on either small and/or macromolecular solutes in the liquid phase and may employ chromatographic, electrophoretic, electrochromatographic separation means, or any combination thereof.