Inducible nitric oxide synthase gene for treatment of disease
US5658565A · kind A · utility
36Cited by
4References
40Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 24, 1994 |
| Grant date | Aug 19, 1997 |
| Priority date | — |
| Expiry date | Jun 24, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/203
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a full-length human hepatocyte iNOS cDNA clone and various gene therapy applications utilizing an iNOS DNA sequence. In preferred embodiments of the disclosed invention, iNOS-directed gene therapy involves specific targeting of a DNA sequence encoding a protein or protein fragment with iNOS biological activity for treating vascular diseases and disorders, antitumor applications and in response to certain microbial infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.