Heteropolymeric protein production methods
US5658760A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 31, 1995 |
| Grant date | Aug 19, 1997 |
| Priority date | — |
| Expiry date | May 31, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/11
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Cultured mammalian cells transfected with new vectors comprising full-length or partial .alpha. and .beta. subunit genomic DNA sequences produce significantly higher levels of dimeric glycoprotein hormone than do cells transfected with .alpha. and .beta. subunit cDNA sequences. In cases where only the cDNA clones are available, the cDNA sequences can be used in new expression vectors comprising introns or other important genomic regions from a homologous or heterologous source.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.