Nicotinic acid esters

US5658910A · kind A · utility

Assignee

• Pharmacia AB · SE

Inventors

• Anders Bjork · Bjärred, SE
• Gunnar Andersson
• Catarina Ludwig · Lund, SE
• Elisabeth Seifert · Uppsala, SE
• Arne Nilsson · Malmö, SE
• Torbjorn Lundstedt · Bjärred, SE
• Lisbeth Abramo · Bjärred, SE
• Goran Pettersson · Hjärup, SE
• Curt Nordvi · Bissenkamp, SE
• Jin Chang Wu · Mariefred, SE

Key dates

• Filing date: May 3, 1995
• Grant date: Aug 19, 1997
• Expiry date: May 3, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel compounds of the formula: ##STR1## wherein R is selected from saturated or unsaturated alkyls, saturated or unsaturated cycloalkyls, heterocyclic compounds, or from (a) or (b) wherein G is carbon wherein G is carbon or nitrogen; m is 0-10, wherein R.sub.1, R.sub.2, and R.sub.3 are the same or different and selected from hydrogen, halogen, alkyl having 1 to 5 carbon atoms, electron donor groups such as alkoxy having 1-5 carbons or hydroxy, electron acceptor groups selected from cyano, nitro, trifluoroalkyl and the pharmacologically acceptable salts thereof; being useful for treating disorder in the central nervous system.