Serine protease and serine protease gene
US5661000A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1995 |
| Grant date | Aug 26, 1997 |
| Priority date | — |
| Expiry date | Feb 8, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/6424
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention offers the serine protease exhibiting a biological activity which a polypeptide having an amino acid sequence shown in FIG. 1 shows, the serine protease precursor where a cleavable peptide or signal peptide connects with the N-terminal of the said serine protease, and the gene encoding them. The serine protease being useful in medical treatment fields can be manufactured in large quantities by the present invention. Moreover, the present invention offers the DNA sequence coding a transcription controlling region contained in the chromosomal gene of the serine protease of a human myeloid cell. This sequence is the transcription controlling region being necessary for the gene expression being specific to a human leukocyte or erythrocyte.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.