Patent · US Expired

Estrogenic compounds as anti-mitotic agents

US5661143A · kind A · utility

40Cited by
4References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 12, 1995
Grant dateAug 26, 1997
Priority date
Expiry dateDec 12, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J63/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The application discloses methods of treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of the general formulae found below in a dosage sufficient to inhibit cell mitosis. The application discloses novel compounds used in the methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.