Structured lipid containing gama-linolenic or dihogamma-linolenic fatty acid residue, a medium chain (C.sub.6 -C.sub.12) fatty acid residue, and a n-3 fatty acid residue
US5661180A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Mar 30, 1995 |
| Grant date | Aug 26, 1997 |
| Priority date | — |
| Expiry date | Mar 30, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/232
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is disclosed structured lipid containing either a gamma-linolenic acid or a dihomogamma-linolenic acid residue, together with an n-3 fatty acid residue and a medium chain fatty acid residue on the same glycerol backbone. This structured lipid is particularly well adapted to the treatment of disease or stress states. The gamma-linolenic or dihomogamma-linolenic acid residues modify the prostanoid synthesis pathway, reducing the level of series "2" prostanoids and elevating the levels of series "1" and "3" prostanoids. The n-3 fatty acid residue enhances the level of series "1" prostanoids as well as increases the production of series "3" prostanoids. The medium chain fatty acid residues enhances the absorption of the structured lipid. There is also disclosed enteral and parenteral diets as well as nutritional supplements containing the structured lipids of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.