Antibodies specific for retinoic acid receptor-.gamma.
US5663303A · kind A · utility
1Cited by
1References
10Claims
0Family size
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Inventors
Key dates
| Filing date | Nov 4, 1991 |
| Grant date | Sep 2, 1997 |
| Priority date | — |
| Expiry date | Nov 4, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/34
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention discloses methods for preparing antibodies which bind to specific isoforms of the human retinoic acid receptor-.gamma. (RAR-.gamma.). In addition, several monoclonal antibodies are described which bind to human RAR-.gamma., but not to mouse or which bind to RAR-.gamma.1, but not to RAR-.gamma.2. Methods and kits are described which allow one to detect the isotype of RAR-.gamma. which is expressed in a test sample. Such methods are useful in determining the tissue specific pattern of expression of various RAR-.gamma. isoforms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.