Processes for preparing functionalized alkyllithium compounds
US5663398A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 12, 1996 |
| Grant date | Sep 2, 1997 |
| Priority date | — |
| Expiry date | Sep 12, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1804
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing functionalized alkyllithium compounds includes reacting in an inert solvent a protected functionalized alkyl halide with an alkali metal in the presence of a catalytic compound of the formula EQU (RR.sup.1 R.sup.2 M.sup.a).sub.y A(R.sup.3).sub.x wherein R, R.sup.1 and R.sup.2 are each independently selected from the group consisting of hydrogen, halogen, alkyl or alkenyl groups containing one to thirteen carbon atoms; R.sup.3 is independently selected from aryl groups containing 6 to 18 carbon atoms, four to six-membered heterocyclic carbon containing groups containing one to two heteroatoms selected from oxygen, nitrogen and sulfur; hydroxyalkyl, alkoxyalkyl, monoalkylaminoalkyl, dialkylaminoalkyl and dialkylphosphinoalkyl groups containing two to thirteen carbon atoms; M.sup.a is an element selected from Group IVA of the Periodic Table of Elements; A is selected from oxygen, sulfur, nitrogen, and phosphorus; x+y equal the valence of A; and x and y may independently have a value from zero to three.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.