Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides

US5665702A · kind A · utility

Assignee

• Biomeasure, Incorporated · US

Inventors

• Shalaby W. Shalaby · Anderson, US
• Steven A. Jackson · Newton, US
• Francis Ignatious · Milford, US
• Jacques-Pierre Moreau · Upton, US

Key dates

• Filing date: Jun 6, 1995
• Grant date: Sep 9, 1997
• Expiry date: Jun 6, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.