Antitumor composition for oral administration
US5665711A · kind A · utility
16Cited by
2References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 12, 1995 |
| Grant date | Sep 9, 1997 |
| Priority date | — |
| Expiry date | Dec 12, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An antitumor composition for oral administration, comprising a 2'-deoxy-2'-methylidenecytidine compound of the formula ##STR1## wherein R is a hydrogen or a halogen, and R.sup.1 and R.sup.2 are the same or different and each is a hydrogen, a halogen or an alkyl having 1 to 4 carbon atoms, an acid addition salt thereof or a hydrate thereof, and a sucrose ester of fatty acid(s). The pharmaceutical composition of the present invention comprising a DMDC compound useful as an antitumor agent based on its remarkable degenerative action on solid tumor shows an improved oral absorption.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.