3-phenylisoquinol-1(2H)-one derivatives their preparation and their therapeutic application

US5665733A · kind A · utility

Assignee

• Synthelabo · FR

Inventors

• Mireille Sevrin · Paris, FR
• Benoit Marabout · Massy, FR
• Jacques Froissant · Châteaudun, FR
• Catherine Guinot · Paris, FR

Key dates

• Filing date: Dec 28, 1995
• Grant date: Sep 9, 1997
• Expiry date: Dec 28, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A compound of formula (I) ##STR1## in which X represents a hydrogen atom, a halogen atom, a trifluoromethyl group, a C.sub.1 -C.sub.3 alkyl group or a C.sub.1 -C.sub.3 alkoxy group in which case two such alkoxy groups X can be present, PA1 Y represents a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.3 alkyl group or a C.sub.1 -C.sub.3 alkoxy group, PA1 R.sub.1 represents C.sub.1 -C.sub.4 alkyl group, and PA1 R represents a hydroxyl group, a methoxy group, an ethoxy group or a group of formula NR.sub.2 R.sub.3 in which R.sub.2 and R.sub.3 each independently represents a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group, or a pharmaceutically acceptable addition salt thereof, processes for their preparation and their therapeutic application.