Biphenyl hydroxamate inhibitors of matrix metalloproteinases
US5665777A · kind A · utility
14Cited by
3References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 14, 1995 |
| Grant date | Sep 9, 1997 |
| Priority date | — |
| Expiry date | Nov 14, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C259/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of formula ##STR1## or a pharmaceutically acceptable salt thereof inhibit matrix metalloproteinases and TNF.alpha. secretion and are useful in the treatment of inflammatory disease states. Also disclosed are matrix metalloproteinases and TNF.alpha. secretion inhibiting compositions and a method for inhibiting matrix metalloproteinases and TNF.alpha. secretion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.