Molecules influencing the shedding of the TNF receptor, their preparation and their use

US5665859A · kind A · utility

Assignee

• YEDA RESEARCH AND DEVELOPMENT CO. LTD. · IL

Inventors

• David Wallach · Rehovot, IL
• Cord Brakebusch · Braunschweig, DE
• Eugene Varfolomeev · Rehovot, IL
• Michael Batkin · Rehovot, IL

Key dates

• Filing date: Oct 12, 1994
• Grant date: Sep 9, 1997
• Expiry date: Oct 12, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Molecules which influence the shedding of the cell-bound p55 Tumor Necrosis Factor receptor (p55-TNF-R), are provided, together with methods of producing them.