Patent · US Expired

Cardiodilatin fragment, process for preparing same and use thereof

US5665861A · kind A · utility

8Cited by
6References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1995
Grant dateSep 9, 1997
Priority date
Expiry dateJun 7, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/834
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Described is a peptide fragment which comprises the amino acid sequence 95-126 of ANF/CDD 1-126 (gamma-hANaP) and is formed in the kidney. The fragment urodilatin (ANF/CDD 95-126) has the following amino acid sequence: ##STR1## wherein R.sup.1 and R.sup.2 each represent further peptide fragments of ANF/CDD 1-126 (gamma-hANaP). In the amino acid sequence R.sup.1 is Thr-Ala-Pro-Arg-Ser-Leu-Arg-Arg-Ser-Ser and R.sup.2 is Asn-Ser-Phe-Arg-Tyr. Further described are processes for the preparation and/or recovery of the new peptide fragment and a medicament containing urodilatin (ANF/CDD 95-126) as well as medical indications of the medicament.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.