Human recombinant collagen in the milk of transgenic animals
US5667839A · kind A · utility
160Cited by
4References
2Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 18, 1994 |
| Grant date | Sep 16, 1997 |
| Priority date | — |
| Expiry date | Jan 18, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/832
- WIPO fieldFood chemistry
- WIPO sectorChemistry
Abstract
Production of human procollagen or collagen in cells which ordinarily do not produce these molecules is effected by constructing expression systems compatible with mammary glands of non-human mammals. For example, expression systems can be microinjected into fertilized oocytes and reimplanted in foster mothers and carried to term in order to obtain transgenic non-human mammals capable of producing milk containing recombinant human procollagen or collagen. Human procollagen or collagen produced in this manner can be made of a single collagen type uncontaminated by other human or non-human collagens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.