Pyruvate thiolester for the prevention of reperfusion injury
US5667962A · kind A · utility
8Cited by
4References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 18, 1996 |
| Grant date | Sep 16, 1997 |
| Priority date | — |
| Expiry date | Mar 18, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C327/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention comprises a novel pyruvate compound for the treatment or prevention of reperfusion injury following ischemia. The novel pyruvate compound is particularly a pyruvate thiolester. Preferably, the thiol is selected from a cysteine or a methionine amino acid. In a particularly preferred form, the compound is an N-acetyl ethyl ester of the cysteine or methionine amino acid. The most preferred compound is: ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.