1,3,4-thiadiazoles and 1,3,4-oxadiazoles as IIb/IIIa antagonists
US5668159A · kind A · utility
39Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 8, 1996 |
| Grant date | Sep 16, 1997 |
| Priority date | — |
| Expiry date | May 8, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
##STR1## This invention relates to improved isoxazoline compounds including, but not limited to 1,3,4-thiadiazoles and 1,3,4-oxadiazoles of the formula which are useful as antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex, to pharmaceutical compositions containing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of platelet aggregation, as thrombolytics, and/or for the treatment of thromboembolic disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.