3-amido-triiodophenyl esters as x-ray contrast agents
US5668196A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 10, 1996 |
| Grant date | Sep 16, 1997 |
| Priority date | — |
| Expiry date | Jul 10, 2016 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to methods of x-ray diagnostic imaging the blood pool, liver, spleen and/or lymph system of a mammal comprising administering a contrast effective amount of a contrast agent having the structure: ##STR1## wherein: n is 0 to 12 PA1 m is 1 or 2 ##STR2## R.sup.1 is X and Z are independently H or NR.sup.2 COR.sup.3 PA1 Y is CO.sub.2, CH.sub.2 O, O or NH and PA1 R.sup.2 and R.sup.3 are independently H, alkyl having from 1 to 12 carbon atoms or aryl having from 6 to 11 carbon atoms, This invention further relates to novel contrast agents having the above structure wherein R.sup.1 is ##STR3## R.sup.2 is H and R.sup.3 is CH.sub.3 to x-ray contrast compositions comprising such agents, and to method of x-ray diagnostic imaging utilizing such agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.