Pharmaceutical spheroid formulation
US5670172A · kind A · utility
126Cited by
12References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 21, 1995 |
| Grant date | Sep 23, 1997 |
| Priority date | — |
| Expiry date | Apr 21, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A controlled release composition including spheroid cores of diltiazem or a pharmaceutically acceptable salt thereof and optionally a spheronizing agent, the cores being coated with a controlled release layer, and a method of manufacturing the same, is disclosed. The spheronizing agent when present is preferably microcrystalline cellulose. Ethylcellulose is a preferred release coating. The controlled release coating preferably contains a plasticizer, a surfactant and a tack-modifier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.