Reiterative method for screening combinatorial libraries
US5670326A · kind A · utility
38Cited by
2References
9Claims
0Family size
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Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Sep 23, 1997 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/962
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Libraries of compounds such as nucleic acids or peptides are contacted with a target molecule and libraries that have at least one compound that bind with at least a minimum activity are determined by a reiterative process in which a change in the rate of recovery (elimination) of compounds that bind to the target indicates that the library contains such a compound. The procedure may also be used to determine indirectly the sequence of such compound by employing sublibraries, each of which have a known entity at a known position of the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.