Patent · US Expired

Halogen, isothiocyanate or azide substituted xanthines

US5670506A · kind A · utility

33Cited by
8References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 5, 1993
Grant dateSep 23, 1997
Priority date
Expiry dateApr 5, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D473/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There is disclosed a compound having the formula: ##STR1## wherein n is an integer from 5 to 9, wherein the core moiety is a heterocylic moiety wherein C.sub.a, C.sub.b, and C.sub.c are an R or S enantiomer or racemic mixture and the C.sub.a, C.sub.b, and C.sub.c carbon atoms are bonded together by a single bond, double bond, ether or ester linkages, wherein R.sub.1, R.sub.2 and R.sub.3 are independently halo, hydroxy, hydrogen, keto, isothiocyano, azide or haloacetoxy with the proviso that at least one of R.sub.1, R.sub.2 or R.sub.3 must be a halo, isothiocyano, azide or haloacetoxy group, wherein R.sub.4 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkenyl, cyclo C.sub.4-6 alkyl, or phenyl, and wherein halo refers to fluoro, chloro, bromo and iodo and salts thereof and pharmaceutical compositions thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.