Tocolytic oxytocin receptor antagonists
US5670509A · kind A · utility
21Cited by
10References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 5, 1995 |
| Grant date | Sep 23, 1997 |
| Priority date | — |
| Expiry date | Apr 5, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula X-Y-Z-R.sup.1 wherein: PA1 X is ##STR1## Y is --CO-- or --SO.sub.2 --; Z is an optional substituent selected from --NH--, --O--, --CHR--, --CH.dbd.CH--, --CH.dbd., --(CH.sub.2).sub.m -- or--CHCHOH--; and PA1 R.sup.1 is --CH.sub.3 --, --CH(CH.sub.3).sub.2, or substituted phenyl are tocolytic oxytocin antagonists useful in the treatment of pre-term labor, stripping labor preparatory to Caesarean delivery and dysmenorrhea.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.