Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders

US5670525A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Klaus Urbahns · Kasai, JP
• Siegfried Goldmann · Wuppertal, DE
• Hans-Georg Heine · Krefeld, DE
• Bodo Junge · Wuppertal, DE
• Rudolf Schohe-Loop · Wuppertal, DE
• Henning Sommermeyer · Neunburg vorm Wald, DE
• Thomas Glaser · Overath, DE
• Reilinde Wittka · Neunburg vorm Wald, DE
• Jean De Vry · Stolberg, DE

Key dates

• Filing date: Aug 22, 1995
• Grant date: Sep 23, 1997
• Expiry date: Aug 22, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/85
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The application relates to substituted 4-phenyl-6-amino-nicotinic acid derivatives for therapeutic use, to novel active compounds and to their use as cerebrally active agents. The active compounds are prepared by oxidizing appropriately substituted dihydropyridines according to customary methods.