Anti-cancer composition comprising rhodacyanine compound and cyclodextrin
US5670530A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Sep 23, 1997 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An anti-cancer composition comprising a rhodacyanine compound and cyclodextrin or derivative thereof, wherein said rhodacyanine compound is selected from the group consisting of compounds represented by the following Formula (I), the cation moiety of which has a log P value of 4.5-12: ##STR1## wherein X.sub.1 and X.sub.2, which may be the same or different, each represents O, S, Se, ##STR2## Y.sub.1 represents O, S, Se, or ##STR3## R.sub.1 and R.sub.3, which may be the same or different, each represents an alkyl group; R.sub.2 represents an alkyl group, an aryl group or a heterocyclic group; Z.sub.1 and Z.sub.2, which may be the same or different, each represents an atomic group necessary to form a 5- or 6-membered ring; L.sub.1, L.sub.2 and L.sub.3, which may be the same or different, each represents a methine group or nitrogen atom and L.sub.1 and R.sub.3 may combine and form a 5- or 6-membered ring; R.sub.4 and R.sub.5, which may be the same or different, each represents an alkyl group; R.sub.6 and R.sub.7, which may be the same or different, each represents an alkyl group or an aryl group; Q represents a pharmaceutically acceptable anion; j and k, which may be the same or diffe…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.