Process for preparing 7-trialkylsilyl baccatin III
US5670658A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 3, 1996 |
| Grant date | Sep 23, 1997 |
| Priority date | — |
| Expiry date | Oct 3, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/188
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a novel process for the preparation of 7-trialkylsilylbaccatin III of general formula: ##STR1## in which the symbols R, which may be identical or different, represent alkyl radicals containing 1 to 4 carbon atoms which are optionally substituted with a phenyl radical, starting with 10-deacetylbaccatin III of formula: ##STR2## In the general formula (I), each of the symbols R preferably represents a straight or branched alkyl radical containing 1 to 4 carbon atoms. Even more particularly, each of the symbols R represents an ethyl radical.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.