Method of treating pain by administering 24 hour oral opioid formulations
US5672360A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 22, 1996 |
| Grant date | Sep 30, 1997 |
| Priority date | — |
| Expiry date | Jul 22, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Patients are treated with 24-hour oral sustained release opioid formulations which, upon administration, provide an initially rapid opioid absorption such that the minimum effective analgesic concentration of the opioid is more quickly achieved. These sustained release opioid formulations include an effective amount of at least one retardant material to cause said opioid analgesic to be released at a such a rate as to provide an analgesic effect after oral administration to a human patient for at least about 24 hours, and are characterized by providing an absorption half-life from 1 to about 8 hours. A method of titrating a human patient utilizing these sustained release opioid formulations is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.