Amorphous paroxetine composition
US5672612A · kind A · utility
25Cited by
4References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 9, 1996 |
| Grant date | Sep 30, 1997 |
| Priority date | — |
| Expiry date | Sep 9, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A free-flowing, amorphous paroxetine hydrochloride-ethanol composition suitable as a therapeutic agent for premature ejaculation can be prepared by dissolving paroxetine free base in a hydrochloric acid-ethanol solution followed by drying. In a preferred embodiment, the amount of ethanol present in the amorphous product is in the range of 1 to 4 weight percent based on paroxetine hydrochloride. The amorphous product is stable and substantially non-hygroscopic.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.