Magnetic protein conjugates, a process for the preparation thereof, and the use thereof

US5672687A · kind A · utility

Assignee

• Behringwerke Aktiengesellschaft · DE

Inventors

• Peter Hermentin · Marburg, DE
• Reiner Donges · Gladenbach, DE
• Karlheinz Enssle · Marburg, DE
• Roland Kurrle · Frankfurt am Main, DE
• Friedrich-Robert Seiler · Marburg, DE

Key dates

• Filing date: Jan 19, 1995
• Grant date: Sep 30, 1997
• Expiry date: Jan 19, 2015

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2446/90
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to magnetic protein conjugates of the formula I ##STR1## in which M represents a dispersible magnetically reacting material or particle which carries aminogroups, Ig represents a protein which carries one or more mercapto groups, and X represents an organic chemical structure which links the two ligands by chemical means, to a process for the preparation of protein conjugates of the formula I, and to the use of conjugates of this type for removing cells or soluble bioorganic molecules or components from aqueous salt solutions or body fluids, and to the use thereof within the framework of a diagnostic method or as a diagnostic aid.