Process for the preparation of N-arylaminoacrylic acid derivatives and the use of N-arylaminoacrylic acid derivatives thus prepared for the preparation of 4-quinolone-3-carboxylic acid derivatives

US5672708A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Gunter Rauchschwalbe · Leverkusen, DE
• Bernhard Beitzke · Bensberg, DE
• Wolfgang Eymann · Neunburg vorm Wald, DE
• Helmut Fiege · Leverkusen, DE

Key dates

• Filing date: Aug 31, 1995
• Grant date: Sep 30, 1997
• Expiry date: Aug 31, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C229/34
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

N-arylaminoacrylic acid derivatives are obtained in good yields and in high purities when benzoylacetic acid derivatives are reacted with N-arylimino ethers. The products thus prepared are used, in particular, for the preparation of 4-quinolone-3-carboxylic acid derivatives, which have an outstanding bactericidal action.