Process for the preparation of 2-substituted cyclopentanones

US5672763A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Nikolaus Muller · Monheim, DE
• Thomas Essert · Overath, DE

Key dates

• Filing date: Jun 21, 1996
• Grant date: Sep 30, 1997
• Expiry date: Jun 21, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C67/343
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

2-Substituted cyclopentanones are prepared by reacting adipic ester with an alkoxide in the presence of an inert solvent, thus obtaining a salt of the cyclopentanone-2-carboxylic ester, alkylating this without isolation, thus obtaining a 2-alkyl-cyclopentanone-2-carboxylic ester and, without isolation, hydrolysing and decarboxylating this by treatment with an acid and heating.