Gas-exchange method of making gas-filled microspheres
US5674469A · kind A · utility
3Cited by
6References
8Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Oct 7, 1997 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/223
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Ultrasonic imaging agents comprising an insoluble gas may be made by a new process of gas exchange. A solution is supersaturated with the insoluble gas and then contacted with a conventional air-filled microsphere suspension in order to effectuate a gas exchange process. The insoluble gas-containing microsphere exhibits increased pressure resistance and stability over microspheres in which the gas exchange was performed passively.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.