Recombinant techniques for production of human brain natriuretic peptide
US5674710A · kind A · utility
30Cited by
6References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1990 |
| Grant date | Oct 7, 1997 |
| Priority date | — |
| Expiry date | Feb 8, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/622
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The cDNA sequence encoding porcine brain natriuretic peptide and related genes encoding canine and human peptides with natriuretic activity are disclosed. The gene is shown to make accessible the DNAs encoding analogous natriuretic peptides in other vertebrate species. The genes encoding these NPs can be used to effect modifications of the sequence to produce alternate forms of the NPs and to provide practical amounts of these proteins. The NPs of the invention can also be synthesized chemically.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.