Dissolved methyllithium-containing composition for use in synthesis reactions

US5677543A · kind A · utility

Assignee

• Metallgesellschaft AG · DE

Inventors

• Wilfried Weiss · Oberursel, DE
• Peter Rittmeyer · Pocking, DE
• Ute Emmel · Frankfurt am Main, DE

Key dates

• Filing date: Jul 7, 1995
• Grant date: Oct 14, 1997
• Expiry date: Jul 7, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F1/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed is a dissolved methyllithium-containing composition for use in synthesis reactions (synthesis composition) and processes of preparing the composition. In the sythesis composition the methyllithium is contained in a solvent of the general formula (I) ##STR1## wherein independently R.sup.1 and R.sup.2 are a hydrogen, methyl or ethyl residue and R.sup.3 and R.sup.4 are a methyl or ethyl residue. To prepare the methyllithium-containing synthesis composition of the invention lithium powder or granular lithium is dispersed in a solvent having the general formula I, methyl halide is added at a controlled rate, the reaction temperature is maintained in the range of from 0.degree. to 60.degree. C., and the resulting lithium halide is separated from the methyllithium solution.