Amino acid derivative
US5679671A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 25, 1995 |
| Grant date | Oct 21, 1997 |
| Priority date | — |
| Expiry date | Jan 25, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06139
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an amino acid derivative having an angiotensin I-converting enzyme inhibition activity, a vasopressin antagonism and an atrial natriuretic peptide hydrolase inhibition activity. This amino acid derivative is represented by the following general formula (I): ##STR1## wherein R.sup.1 represents a hydrogen atom or an acyl group; R.sup.2 represents a hydrogen atom, a lower alkyl group, a cycloalkyl group, an ary group which may have a substituent, a heteroaryl group which may have a substituent, an arylalkyl group which may have a substituent or a heteroarylalkyl group which may have a substituent; PA1 m and n represent each independently an integer of 0, 1 or 2 and PA1 J represents a cyclic group having an angiotensin I-converting enzyme inhibition activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.