Method of preparing polyalkylene oxide carboxylic acids
US5681567A · kind A · utility
184Cited by
16References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 13, 1996 |
| Grant date | Oct 28, 1997 |
| Priority date | — |
| Expiry date | Aug 13, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G65/337
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to methods of preparing high purity polyalkylene oxide carboxylic acids. The methods include reacting a polyalkylene oxide such as polyethylene glycol with a t-butyl haloacetate in the presence of a base followed by treatment with an acid such as trifluoroacetic acid. The resultant polymer carboxylic acids are of sufficient purity so that expensive and time containing purification steps required for pharmaceutical grade polymers are avoided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.